Barbara Linda BehrendsEvaluation des extravaskulären arteriellen Gefäßverschlusssystems 6F EXOSEAL nach antegrader Punktion der Arteria femoralis communis

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This doctor’s thesis deals with the evaluation of safety, efficacy, patient satisfaction and patient comfort of the extravascular, bioabsorbable, arterial closure device 6F EXOSEAL (Cordis Corporation) after antegrade puncture of the common femoral artery. To examine the indication range in the daily routine and to discover possible risk factors for the use of EXOSEAL patients with risk factors for access site-related complications (e.g. increased body-mass-index, calcified access site, increased bleeding tendency, etc.) were not excluded.

In a single-center, not randomized, prospective, single-arm study 59 consecutive patients were evaluated in terms of technical success (98.3%), major and minor adverse events (1.7% and 5.1%), pain during implantation, satisfaction and the preference between 6F EXOSEAL and an eventual previous manual compression of the access site.

In addition, an overview of the traditional manual compression, the established arterial closure devices (such as AngioSeal, Perclose, StarClose) and further studies on EXOSEAL was provided.

In conclusion sealing antegrade puncture of the common femoral artery with 6F EXOSEAL was safe with an excellent technical success, low rates of adverse events, high patient satisfaction and high patient comfort. No significant risk factors could be evaluated.

Ihr Werk im Verlag Dr. Kovač

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